Technical exchange

Foreign media: study says genetically modified chickens may be resistant to bird flu

Release time:

Jun 12,2019


Foreign media said that British scientists have used gene editing technology on chicken cells cultured in the laboratory to prevent the spread of avian influenza. This is a key step in the development of genetically modified chickens that can prevent the outbreak of human influenza.

According to Reuters6Month3In this latest study, researchers from Imperial College and the Roslin Institute at the University of Edinburgh, by changing the chicken in cells cultured in the laboratory, reported thatDNAto prevent the bird flu virus from surviving and replicating in that cell.

Mike McGrew of the Roslin Institute, who co-led the research, revealed that the next step will be to breed the genetically modified chickens.

 "This is an important development and shows that we may be able to use gene editing technology to breed chickens that are resistant to avian influenza." McGrew said in a statement.

 "We haven't made that kind of chicken yet. We need to confirm,DNAWhether the change will have other effects on the chicken before we can move on to the next step.”

Reported that in future research, the research team hopes to use gene editing technology to remove birdsDNAIn a certain part, this partDNAIt is responsible for directing the synthesis of proteins on which influenza virus infects the host.

Laboratory studies of cells lacking the gene have shown that they can ward off the flu virus-preventing it from entering, replicating and spreading.

2009Year2010year,H1N1Influenza pandemics caused by viruses have caused a large number of deaths worldwide.1918The Spanish flu pandemic5000Thousands died.

Wendy Buckley, a professor of virology at Imperial College, who worked with McGrew, said that the original intention of cultivating genetically modified anti-influenza chickens is to "prevent the next influenza pandemic with poultry as the source of infection".


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